We cordially invite you to the next PIVAC meeting The 21st International Conference on Progress in Vaccination Against Cancer” (PIVAC-22) which will be held on 26 ^th –28 ^th September 2022, Molecular Biotechnology Center, “Guido Tarone”. The meeting will cover the most recent advances in the field of cancer immunotherapy, with a focus on the tumor microenvironment, addressing how alterations to its molecular and metabolic features and to the microbiota impact the response to immunotherapy. Our main objectives are to gather, share and exchange experiences and ideas, promote interactions between speakers and participants and encourage stimulating discussions, provide network opportunities and stimulate new collaborations. We look forward to welcoming you to Torino.